ZO® Skin Health


ZO® Skin Health by Zein Obagi, MD is turning skin care inside out. Instead of expecting topical lotions and creams to provide quick fixes and one-shot wonders, ZO® Skin Health products work from the inside out, activating and stimulating your skin’s cells to nourish, repair and maintain themselves. It’s not a miracle, really. It’s just the way that nature intended.

ZO®Skin Health uses thf_11zeine most potent ingredients, high concentrations, pure retinol, advanced peptides, and powerful anti-oxidents. Some of the formulas are admittedly over the top. Because to win the battle on aging, you have to give it your best shot.



zo exf cleanserCONCERNS
Oily, acne-prone skin, blemishes. Tendency to have blackheads and whiteheads. Sudden and unexpected acne flare-ups.

Cleansing is an important first step for all skin types, but for oily, acne-prone skin, it’s critical. The key to managing oily skin is gently exfoliating dull, dry skin cells that trap bacteria; reducing excess oil; and neutralizing free radicals. Offects® Exfoliating Cleanser does all of that and goes one step further–it boosts collagen production. Includes encapsulated beads with Vitamin E – the most important anti-oxidant for healthy skin. Dirt, make-up and premature aging…down the drain.



Clogged pores, acne-prone skin, blackheads, oily complexion

Too much sebum—oil which is found on the surface of the skin–causes oily skin and the problems associated with it. When combined with bacteria, excess sebum will likely result in frequent acne flare-ups, blackheads, whiteheads and enlarged pores. Offects® TE-Pads are hydrated in 2% Salicylic Acid – the highest over-the-counter concentration – which gently exfoliates pore-clogging dead skin cells and unclogs congested pores. Botanical extracts calm inflammation and soothe irritation. Use twice a day for both prevention and treatment. You’ll look younger. Healthier. Maybe even a little smarter.

Salicylic Acid: acne-fighting ingredient to deeply penetrate pores, slough dead skin cells and remove excess dirt that can clog pores and cause breakouts.


CONCERNSexfolliating-polish close
The outermost layer of your skin is actually dead skin cells. As your skin creates new cells that emerge on the surface, the old ones should slough off. However, as we age, this process slows, and the dead skin cells may accumulate on the surface, causing dry or dull patches of skin, sun spots, rough skin, uneven skin tone, fine lines and wrinkles.

Round magnesium crystals exfoliate dead skin cells, increase epidermal turnover and create a clearer, smoother, more even-toned complexion. But the benefits go deeper than that. Vitamins A, C, C-Esters and E provide powerful anti-oxidant protection. Then active ingredients can penetrate your skin and work harder, deeper and faster.


  • Magnesium Crystals: remove dead surface cells to allow for better penetration and enhanced cellular turnover
  • Vitamin A: helps increase cellular turnover and boosts collagen production to help rejuvenate skin’s texture
  • Vitamin C & C Esters: potent anti-oxidants that stimulate collagen synthesis and protect skin by reducing free radicals
  • Vitamin E: the antioxidant most frequently recommended by dermatologists to fight free radicals and repair damaged skin cells



Pre-mature aging, lines, wrinkles, loss of elasticity, texture and firmness

Ossential® Daily Power Defense uses DNA repair enzymes to enhance your skin’s recovery capabilities. These special enzymes attach directly to your own DNA molecules and repair oxidative damage caused by UV exposure. It works all day with time-release retinol, enzymes and anti-oxidants to repair damaged cells and protect against future damage.


  • Retinol: a pure derivative of Vitamin A and the most vital component of any anti-aging skincare program. It is clinically proven to be the most effective anti-aging ingredient to decrease the appearance of fine lines and wrinkles, even skin tone and increase epidermal thickness.
  • Ultrasomes & Roxisomes: repair oxidative damage to DNA and help dramatically reduce future photodamage.


CONCERNSZo Skin Health Radical Night Repair
Chronological or environmental skin aging. Deeper lines and wrinkles around the eyes and forehead, tiny wrinkles around the mouth and lips, hyperpigmentation (age spots, sun damage), thinning skin with reduced elasticity/firmness.

As we age, skin cells go dormant and cellular generation slows; what used to take 30 days now takes considerably longer. Old, dull, damaged skin cells remain on the surface of the skin. To accelerate cellular turnover, Ossential® Radical Night Repair Plus features a potent concentration of retinol. After it has penetrated our skin, retinol reacts with natural enzymes to convert to trans-retinoic acid, which is a usable form of Vitamin A. Skin can then generate new cells and produce more collagen. This activity makes older cells rise to the surface and exfoliate. As new skin cells emerge, skin appears younger, healthier, more even-toned and radiant.

Because of the high concentration of active ingredients, people who have the following conditions are not suitable candidates:

  • Sensitive skin that is easily irritated
  • Pregnant or lactating
  • Concurrent use of prescription acne medication
  • Daily use of a retinoid


  • 1.0% concentration of retinol — Ossential® Radical Night Repair Plus features the highest concentration of retinol in an over-the-counter product (6X-10X higher than traditional retinol products). Retinol causes new collagen to be formed in chronologically-aged skin and skin damaged by UV rays. It is the most effective topical anti-aging ingredient, because it assists in the process of repairing and rebuilding collagen. Given the high concentration of retinol, ZoSkinHealth-373x500Ossential® Radical Night Repair Plus works faster, and more effectively, than any other anti-aging product.Products that have a low concentration of retinol—e.g, .10% to .15%, produce less retinol cascade (the process by which special enzymes convert the retinol to the active metabolite, retinoic acid). When this conversion rate is low, very little retinoic acid becomes bio-available to the cells. A high concentration of retinol (such as with 1.0%) increases the conversion rate of retinol-to-retinoic acid. The higher the concentration of retinol, therefore, the greater the conversion to retinoic acid, and the better the result. Scientists agree that an even higher concentration (for ex., 2% or 3% or 4%) would be even more effective, however the product would be extremely and unacceptably irritating. 1% is the ideal “cap rate”—the greatest concentration of retinol, with little to no irritation.
  • Time-Released Microspheres. Traditional retinol products cause a sudden release and “downpour” of retinol—which can be irritating. That’s why manufacturers use a very low concentration of retinol. ZO® Skin Health’s Radical Night Repair Plus uses a unique delivery system–the retinol is encapsulated in a time-released microsphere. So unlike the “downpour”, micro-spheres causes a slow, steady, continuous “drizzle”.
  • Anhydrous (water-free) formula increases the potency of active ingredients.
  • Skinasensyl®, a peptide that increases skin’s natural tolerance threshold. Users are much less likely to experience any discomfort, which is especially beneficial to over-reactive and sensitive skin.


Lines, wrinkles, loss of tone, elasticity, texture and firmness

This is your one-two punch to fight aging. Two powerful proprietary peptides, retinol and amino acids boost collagen and stimulate cellular function. You can reduce collagen degradation, restore skin elasticity – translation: you’ll lose the lines and wrinkles and look younger! Soothing, calming gel formula.


  • Epidermal Growth Factor: engineered to dramatically increase cell-regeneration and visibly reduce the appearance of fine lines and discoloration.
  • Retinol: a pure derivative of Vitamin A and the most vital component of any anti-aging skincare program. It is clinically proven to be the most effective anti-aging ingredient to decrease the appearance of fine lines and wrinkles, even skin tone and increase epidermal thickness.
  • Proprietary Lipopeptides: stimulate collagen and elastin.




Irritation, sensitivity, or dryness

There’s no frou-frou in any skin care product developed by Zein Obagi, MD. This is the first functional moisturizer ever produced, because it does more than hydrate and give your skin a false sense of security. This crème is packed with pure retinol, powerful anti-oxidants and a soothing agents to repair the skin barrier and rejuvenate the skin. Oh, and one more thing. It’s a great all-day hydrator, too.


  • Hyaluronic Acid: creates a barrier proven to lock in moisture.
  • Retinol: a pure derivative of Vitamin A and the most vital component of any anti-aging skincare program. It is clinically proven to be the most effective anti-aging ingredient to decrease the appearance of fine lines and wrinkles, even skin tone and increase epidermal thickness.
  • Photosomes: reduces the appearance of discolorations and inflammation, visibly improving skin’s tone and overall skin health.
  • Canadian Willowherb and Oat extracts: calm and soothe skin irritation.


Premature aging symptoms intensified by dull dry skinommerse-overnight-recovery-creme

While you sleep, your skin becomes more active, repairing and regenerating skin cells. This is the most important time to strengthen and nourish your skin. Ommerse Overnight Recovery Crème is the natural counterpoint to an active day – a little bit of R and R to calm and nourish the skin. It’s not sheer indulgence, though. While you sleep, retinol works to reduce fine lines and wrinkles, ceramides nourish and calming agents protect against inflammation.


  • Retinol: a pure derivative of Vitamin A and the most vital component of any anti-aging skincare program. It is clinically proven to be the most effective anti-aging ingredient to decrease the appearance of fine lines and wrinkles, even skin tone and increase epidermal thickness.
  • Canadian Willowherb: clinically proven to significantly reduce chemical and UV-induced redness, inflammation and irritation.
  • Squalane: increases skin respiration and prevents water loss from the surface, restoring natural oils.
  • Shea Butter: improves skin’s softness and suppleness.



Fight the #1 cause of wrinkles, age spots and loss of firmness

Oclipse® was named the #1 best sunscreen by the online beauty authority. Not just because it’s a great sunscreen (there are lots of those!) and not just because it multi-tasks as a makeup primer (although that’s nice too!) and not just because it’s tinted (bye bye white and pasty sunscreen!). The best part: it’s something you’ll want to wear every day of your life (have you ever said that about a sunscreen?). Features natural melanin and broad spectrum UVA/UVB protection. If you’re going to do just one nice thing for your skin this is it.


  • Zinc Oxide and Titanium Dioxide: clinically proven non-irritating UVA & UVB blockers.
  • Proprietary Lipopeptide: stimulates collagen and elastin.
  • Humectants and Emollients: moisturizing agents.
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Where Beautiful Skin Begins